This application is conducting a wide search for small untranslated RNAs (sRNAs) that regulate several processes such as secretion or virulence in bacteria. The kingdom-wide prediction and annotation of sRNA encoding genes involves a variety of individual programs that are executed in the proper order using Pegasus. These involve the prediction of Rho-independent transcriptional terminators, BLAST (Basic Local Alignment Search Tools) comparisons of the inter genetic regions of different replicons and the annotations of any sRNAs that are found. The application is launch via a web portal.
Scientists: Jonathan Livny (Harvard)